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New Insights into the Role of Mitochondrial Dynamics and Autophagy during Oxidative Stress and Aging in the Heart
The heart is highly sensitive to the aging process. In the elderly, the heart tends to become hypertrophic and fibrotic. Stiffness increases with ensuing systolic and diastolic dysfunction. Aging also affects the cardiac response to stress. At the molecular level, the aging process is associated wit...
Autores principales: | Ikeda, Yoshiyuki, Sciarretta, Sebastiano, Nagarajan, Narayani, Rubattu, Speranza, Volpe, Massimo, Frati, Giacomo, Sadoshima, Junichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124219/ https://www.ncbi.nlm.nih.gov/pubmed/25132912 http://dx.doi.org/10.1155/2014/210934 |
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