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Adenosine triphosphatases of thermophilic archaeal double-stranded DNA viruses
Adenosine triphosphatases (ATPases) of double-stranded (ds) DNA archaeal viruses are structurally related to the AAA+ hexameric helicases and translocases. These ATPases have been implicated in viral life cycle functions such as DNA entry into the host, and viral genome packaging into preformed proc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124505/ https://www.ncbi.nlm.nih.gov/pubmed/25105011 http://dx.doi.org/10.1186/2045-3701-4-37 |
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author | Happonen, Lotta J Erdmann, Susanne Garrett, Roger A Butcher, Sarah J |
author_facet | Happonen, Lotta J Erdmann, Susanne Garrett, Roger A Butcher, Sarah J |
author_sort | Happonen, Lotta J |
collection | PubMed |
description | Adenosine triphosphatases (ATPases) of double-stranded (ds) DNA archaeal viruses are structurally related to the AAA+ hexameric helicases and translocases. These ATPases have been implicated in viral life cycle functions such as DNA entry into the host, and viral genome packaging into preformed procapsids. We summarize bioinformatical analyses of a wide range of archaeal ATPases, and review the biochemical and structural properties of those archaeal ATPases that have measurable ATPase activity. We discuss their potential roles in genome delivery into the host, virus assembly and genome packaging in comparison to hexameric helicases and packaging motors from bacteriophages. |
format | Online Article Text |
id | pubmed-4124505 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-41245052014-08-08 Adenosine triphosphatases of thermophilic archaeal double-stranded DNA viruses Happonen, Lotta J Erdmann, Susanne Garrett, Roger A Butcher, Sarah J Cell Biosci Review Adenosine triphosphatases (ATPases) of double-stranded (ds) DNA archaeal viruses are structurally related to the AAA+ hexameric helicases and translocases. These ATPases have been implicated in viral life cycle functions such as DNA entry into the host, and viral genome packaging into preformed procapsids. We summarize bioinformatical analyses of a wide range of archaeal ATPases, and review the biochemical and structural properties of those archaeal ATPases that have measurable ATPase activity. We discuss their potential roles in genome delivery into the host, virus assembly and genome packaging in comparison to hexameric helicases and packaging motors from bacteriophages. BioMed Central 2014-07-23 /pmc/articles/PMC4124505/ /pubmed/25105011 http://dx.doi.org/10.1186/2045-3701-4-37 Text en Copyright © 2014 Happonen et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Happonen, Lotta J Erdmann, Susanne Garrett, Roger A Butcher, Sarah J Adenosine triphosphatases of thermophilic archaeal double-stranded DNA viruses |
title | Adenosine triphosphatases of thermophilic archaeal double-stranded DNA viruses |
title_full | Adenosine triphosphatases of thermophilic archaeal double-stranded DNA viruses |
title_fullStr | Adenosine triphosphatases of thermophilic archaeal double-stranded DNA viruses |
title_full_unstemmed | Adenosine triphosphatases of thermophilic archaeal double-stranded DNA viruses |
title_short | Adenosine triphosphatases of thermophilic archaeal double-stranded DNA viruses |
title_sort | adenosine triphosphatases of thermophilic archaeal double-stranded dna viruses |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124505/ https://www.ncbi.nlm.nih.gov/pubmed/25105011 http://dx.doi.org/10.1186/2045-3701-4-37 |
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