The Alliance of Mesenchymal Stem Cells, Bone, and Diabetes

Bone fragility has emerged as a new complication of diabetes. Several mechanisms in diabetes may influence bone homeostasis by impairing the action between osteoblasts, osteoclasts, and osteocytes and/or changing the structural properties of the bone tissue. Some of these mechanisms can potentially...

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Autores principales: Napoli, Nicola, Strollo, Rocky, Paladini, Angela, Briganti, Silvia I., Pozzilli, Paolo, Epstein, Sol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124651/
https://www.ncbi.nlm.nih.gov/pubmed/25140176
http://dx.doi.org/10.1155/2014/690783
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author Napoli, Nicola
Strollo, Rocky
Paladini, Angela
Briganti, Silvia I.
Pozzilli, Paolo
Epstein, Sol
author_facet Napoli, Nicola
Strollo, Rocky
Paladini, Angela
Briganti, Silvia I.
Pozzilli, Paolo
Epstein, Sol
author_sort Napoli, Nicola
collection PubMed
description Bone fragility has emerged as a new complication of diabetes. Several mechanisms in diabetes may influence bone homeostasis by impairing the action between osteoblasts, osteoclasts, and osteocytes and/or changing the structural properties of the bone tissue. Some of these mechanisms can potentially alter the fate of mesenchymal stem cells, the initial precursor of the osteoblast. In this review, we describe the main factors that impair bone health in diabetic patients and their clinical impact.
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spelling pubmed-41246512014-08-19 The Alliance of Mesenchymal Stem Cells, Bone, and Diabetes Napoli, Nicola Strollo, Rocky Paladini, Angela Briganti, Silvia I. Pozzilli, Paolo Epstein, Sol Int J Endocrinol Review Article Bone fragility has emerged as a new complication of diabetes. Several mechanisms in diabetes may influence bone homeostasis by impairing the action between osteoblasts, osteoclasts, and osteocytes and/or changing the structural properties of the bone tissue. Some of these mechanisms can potentially alter the fate of mesenchymal stem cells, the initial precursor of the osteoblast. In this review, we describe the main factors that impair bone health in diabetic patients and their clinical impact. Hindawi Publishing Corporation 2014 2014-07-16 /pmc/articles/PMC4124651/ /pubmed/25140176 http://dx.doi.org/10.1155/2014/690783 Text en Copyright © 2014 Nicola Napoli et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Napoli, Nicola
Strollo, Rocky
Paladini, Angela
Briganti, Silvia I.
Pozzilli, Paolo
Epstein, Sol
The Alliance of Mesenchymal Stem Cells, Bone, and Diabetes
title The Alliance of Mesenchymal Stem Cells, Bone, and Diabetes
title_full The Alliance of Mesenchymal Stem Cells, Bone, and Diabetes
title_fullStr The Alliance of Mesenchymal Stem Cells, Bone, and Diabetes
title_full_unstemmed The Alliance of Mesenchymal Stem Cells, Bone, and Diabetes
title_short The Alliance of Mesenchymal Stem Cells, Bone, and Diabetes
title_sort alliance of mesenchymal stem cells, bone, and diabetes
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124651/
https://www.ncbi.nlm.nih.gov/pubmed/25140176
http://dx.doi.org/10.1155/2014/690783
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