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Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model

PURPOSE: Despite advances in surgical treatment options, large rotator cuff (r-c) tears still represent a challenge for orthopedic surgeons. The purpose of this study was to evaluate the temporary and spatial histological incorporation of fascia lata allografts, used for bridging artificially create...

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Autores principales: Varvitsiotis, Dimitrios, Papaspiliopoulos, Athanasios, Vlachou, Vasiliki, Feroussis, John, Papalois, Apostolos, Papacharalampous, Xenofon, Soucacos, Panayotis N., Zoubos, Aristides
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124672/
https://www.ncbi.nlm.nih.gov/pubmed/25114414
http://dx.doi.org/10.4103/0973-6042.137526
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author Varvitsiotis, Dimitrios
Papaspiliopoulos, Athanasios
Vlachou, Vasiliki
Feroussis, John
Papalois, Apostolos
Papacharalampous, Xenofon
Soucacos, Panayotis N.
Zoubos, Aristides
author_facet Varvitsiotis, Dimitrios
Papaspiliopoulos, Athanasios
Vlachou, Vasiliki
Feroussis, John
Papalois, Apostolos
Papacharalampous, Xenofon
Soucacos, Panayotis N.
Zoubos, Aristides
author_sort Varvitsiotis, Dimitrios
collection PubMed
description PURPOSE: Despite advances in surgical treatment options, large rotator cuff (r-c) tears still represent a challenge for orthopedic surgeons. The purpose of this study was to evaluate the temporary and spatial histological incorporation of fascia lata allografts, used for bridging artificially created defects of the r-c. MATERIALS AND METHODS: Seventy-two rabbits were divided into two groups and a supraspinatus tendinous defect was created. Half of the rabbit population underwent repair only, while in the other half, the defect was bridged utilizing fascia lata allograft. The animals were euthanized at 2, 4, and 6 weeks postoperative. Half of the specimens were evaluated histologically and the other half underwent mechanical testing. RESULTS: There was an increased remodeling activity, fibroblastic in growth and strong presence of collagen fibers observed at 6 weeks on both groups. A gradually increasing mechanical strength was noticed by week 6 and increased toughness was also found at the same time period. There was no significant difference observed between the two groups regarding their histological and mechanical properties. CONCLUSIONS: In the difficult scenario of a large irreparable tear where the simple suture of the remaining r-c is impossible, allograft bridging, could be used with satisfactory results. CLINICAL RELEVANCE: Treatment Study, Level 1.
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spelling pubmed-41246722014-08-11 Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model Varvitsiotis, Dimitrios Papaspiliopoulos, Athanasios Vlachou, Vasiliki Feroussis, John Papalois, Apostolos Papacharalampous, Xenofon Soucacos, Panayotis N. Zoubos, Aristides Int J Shoulder Surg Original Article PURPOSE: Despite advances in surgical treatment options, large rotator cuff (r-c) tears still represent a challenge for orthopedic surgeons. The purpose of this study was to evaluate the temporary and spatial histological incorporation of fascia lata allografts, used for bridging artificially created defects of the r-c. MATERIALS AND METHODS: Seventy-two rabbits were divided into two groups and a supraspinatus tendinous defect was created. Half of the rabbit population underwent repair only, while in the other half, the defect was bridged utilizing fascia lata allograft. The animals were euthanized at 2, 4, and 6 weeks postoperative. Half of the specimens were evaluated histologically and the other half underwent mechanical testing. RESULTS: There was an increased remodeling activity, fibroblastic in growth and strong presence of collagen fibers observed at 6 weeks on both groups. A gradually increasing mechanical strength was noticed by week 6 and increased toughness was also found at the same time period. There was no significant difference observed between the two groups regarding their histological and mechanical properties. CONCLUSIONS: In the difficult scenario of a large irreparable tear where the simple suture of the remaining r-c is impossible, allograft bridging, could be used with satisfactory results. CLINICAL RELEVANCE: Treatment Study, Level 1. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4124672/ /pubmed/25114414 http://dx.doi.org/10.4103/0973-6042.137526 Text en Copyright: © International Journal of Shoulder Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Varvitsiotis, Dimitrios
Papaspiliopoulos, Athanasios
Vlachou, Vasiliki
Feroussis, John
Papalois, Apostolos
Papacharalampous, Xenofon
Soucacos, Panayotis N.
Zoubos, Aristides
Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model
title Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model
title_full Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model
title_fullStr Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model
title_full_unstemmed Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model
title_short Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model
title_sort fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124672/
https://www.ncbi.nlm.nih.gov/pubmed/25114414
http://dx.doi.org/10.4103/0973-6042.137526
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