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Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model
PURPOSE: Despite advances in surgical treatment options, large rotator cuff (r-c) tears still represent a challenge for orthopedic surgeons. The purpose of this study was to evaluate the temporary and spatial histological incorporation of fascia lata allografts, used for bridging artificially create...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124672/ https://www.ncbi.nlm.nih.gov/pubmed/25114414 http://dx.doi.org/10.4103/0973-6042.137526 |
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author | Varvitsiotis, Dimitrios Papaspiliopoulos, Athanasios Vlachou, Vasiliki Feroussis, John Papalois, Apostolos Papacharalampous, Xenofon Soucacos, Panayotis N. Zoubos, Aristides |
author_facet | Varvitsiotis, Dimitrios Papaspiliopoulos, Athanasios Vlachou, Vasiliki Feroussis, John Papalois, Apostolos Papacharalampous, Xenofon Soucacos, Panayotis N. Zoubos, Aristides |
author_sort | Varvitsiotis, Dimitrios |
collection | PubMed |
description | PURPOSE: Despite advances in surgical treatment options, large rotator cuff (r-c) tears still represent a challenge for orthopedic surgeons. The purpose of this study was to evaluate the temporary and spatial histological incorporation of fascia lata allografts, used for bridging artificially created defects of the r-c. MATERIALS AND METHODS: Seventy-two rabbits were divided into two groups and a supraspinatus tendinous defect was created. Half of the rabbit population underwent repair only, while in the other half, the defect was bridged utilizing fascia lata allograft. The animals were euthanized at 2, 4, and 6 weeks postoperative. Half of the specimens were evaluated histologically and the other half underwent mechanical testing. RESULTS: There was an increased remodeling activity, fibroblastic in growth and strong presence of collagen fibers observed at 6 weeks on both groups. A gradually increasing mechanical strength was noticed by week 6 and increased toughness was also found at the same time period. There was no significant difference observed between the two groups regarding their histological and mechanical properties. CONCLUSIONS: In the difficult scenario of a large irreparable tear where the simple suture of the remaining r-c is impossible, allograft bridging, could be used with satisfactory results. CLINICAL RELEVANCE: Treatment Study, Level 1. |
format | Online Article Text |
id | pubmed-4124672 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-41246722014-08-11 Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model Varvitsiotis, Dimitrios Papaspiliopoulos, Athanasios Vlachou, Vasiliki Feroussis, John Papalois, Apostolos Papacharalampous, Xenofon Soucacos, Panayotis N. Zoubos, Aristides Int J Shoulder Surg Original Article PURPOSE: Despite advances in surgical treatment options, large rotator cuff (r-c) tears still represent a challenge for orthopedic surgeons. The purpose of this study was to evaluate the temporary and spatial histological incorporation of fascia lata allografts, used for bridging artificially created defects of the r-c. MATERIALS AND METHODS: Seventy-two rabbits were divided into two groups and a supraspinatus tendinous defect was created. Half of the rabbit population underwent repair only, while in the other half, the defect was bridged utilizing fascia lata allograft. The animals were euthanized at 2, 4, and 6 weeks postoperative. Half of the specimens were evaluated histologically and the other half underwent mechanical testing. RESULTS: There was an increased remodeling activity, fibroblastic in growth and strong presence of collagen fibers observed at 6 weeks on both groups. A gradually increasing mechanical strength was noticed by week 6 and increased toughness was also found at the same time period. There was no significant difference observed between the two groups regarding their histological and mechanical properties. CONCLUSIONS: In the difficult scenario of a large irreparable tear where the simple suture of the remaining r-c is impossible, allograft bridging, could be used with satisfactory results. CLINICAL RELEVANCE: Treatment Study, Level 1. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4124672/ /pubmed/25114414 http://dx.doi.org/10.4103/0973-6042.137526 Text en Copyright: © International Journal of Shoulder Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Varvitsiotis, Dimitrios Papaspiliopoulos, Athanasios Vlachou, Vasiliki Feroussis, John Papalois, Apostolos Papacharalampous, Xenofon Soucacos, Panayotis N. Zoubos, Aristides Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model |
title | Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model |
title_full | Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model |
title_fullStr | Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model |
title_full_unstemmed | Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model |
title_short | Fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model |
title_sort | fascia lata allograft bridging of a rotator cuff tear in a rabbit animal model |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124672/ https://www.ncbi.nlm.nih.gov/pubmed/25114414 http://dx.doi.org/10.4103/0973-6042.137526 |
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