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Utility of Diagnostic Imaging in the Diagnosis and Management of Schistosomiasis
Diagnosis of schistosomiasis is made by demonstration of the parasite ova in stools, urine,and biopsy specimens from affected organs, or presence of antibodies to the different stages of the parasite or antigens circulating in body fluids by serologic techniques. DNA of schistosomes can now also be...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124748/ https://www.ncbi.nlm.nih.gov/pubmed/25110719 http://dx.doi.org/10.4172/2327-5073.1000142 |
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author | Olveda, David U. Olveda, Remigio M. Lam, Alfred K. Chau, Thao N.P. Li, Yuesheng Gisparil, Angelo Don Ross, Allen G.P. |
author_facet | Olveda, David U. Olveda, Remigio M. Lam, Alfred K. Chau, Thao N.P. Li, Yuesheng Gisparil, Angelo Don Ross, Allen G.P. |
author_sort | Olveda, David U. |
collection | PubMed |
description | Diagnosis of schistosomiasis is made by demonstration of the parasite ova in stools, urine,and biopsy specimens from affected organs, or presence of antibodies to the different stages of the parasite or antigens circulating in body fluids by serologic techniques. DNA of schistosomes can now also be detected in serum and stool specimens by molecular technique.However, these tests are unable to determine the severity of target organ pathology and resultant complications. Accurate assessment of schistosome-induced morbidities is now made with the use of imaging techniques like ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI). US has made major contributions in the diagnosis of hepatosplenic and urinary form of disease. This imaging method provides real time results, is portable (can be carried to the bed side and the field) and is lower in cost than other imaging techniques. Typical findings in hepatosplenic schistosomiasis by US include: hyperechoic fibrotic bands along the portal vessels (Symmer’s fibrosis), reduction in the size of the right lobe, hypertrophy of the left lobe, splenomegaly, and ascites. More advanced ultrasound equipment like the colour Doppler ultrasound can characterize portal vein perfusion, a procedure that is critical for the prediction of disease prognosis and for treatment options for complicated portal hypertension. Although CT and MRI are more expensive, are hospital based, and require highly additional specially-trained personnel, they provide more accurate description of the pathology, not only in hepatosplenic and urinary forms of schistosomiasis, but also in the diagnosis of ectopic forms of the disease,particularly involving thebrain and spinal cord. MRI demonstrates better tissue differentiation and lack of exposure to ionizing radiation compared with CT. |
format | Online Article Text |
id | pubmed-4124748 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
record_format | MEDLINE/PubMed |
spelling | pubmed-41247482014-08-07 Utility of Diagnostic Imaging in the Diagnosis and Management of Schistosomiasis Olveda, David U. Olveda, Remigio M. Lam, Alfred K. Chau, Thao N.P. Li, Yuesheng Gisparil, Angelo Don Ross, Allen G.P. Clin Microbiol Article Diagnosis of schistosomiasis is made by demonstration of the parasite ova in stools, urine,and biopsy specimens from affected organs, or presence of antibodies to the different stages of the parasite or antigens circulating in body fluids by serologic techniques. DNA of schistosomes can now also be detected in serum and stool specimens by molecular technique.However, these tests are unable to determine the severity of target organ pathology and resultant complications. Accurate assessment of schistosome-induced morbidities is now made with the use of imaging techniques like ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI). US has made major contributions in the diagnosis of hepatosplenic and urinary form of disease. This imaging method provides real time results, is portable (can be carried to the bed side and the field) and is lower in cost than other imaging techniques. Typical findings in hepatosplenic schistosomiasis by US include: hyperechoic fibrotic bands along the portal vessels (Symmer’s fibrosis), reduction in the size of the right lobe, hypertrophy of the left lobe, splenomegaly, and ascites. More advanced ultrasound equipment like the colour Doppler ultrasound can characterize portal vein perfusion, a procedure that is critical for the prediction of disease prognosis and for treatment options for complicated portal hypertension. Although CT and MRI are more expensive, are hospital based, and require highly additional specially-trained personnel, they provide more accurate description of the pathology, not only in hepatosplenic and urinary forms of schistosomiasis, but also in the diagnosis of ectopic forms of the disease,particularly involving thebrain and spinal cord. MRI demonstrates better tissue differentiation and lack of exposure to ionizing radiation compared with CT. 2014-04-15 /pmc/articles/PMC4124748/ /pubmed/25110719 http://dx.doi.org/10.4172/2327-5073.1000142 Text en © 2014 Olveda DU, et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Article Olveda, David U. Olveda, Remigio M. Lam, Alfred K. Chau, Thao N.P. Li, Yuesheng Gisparil, Angelo Don Ross, Allen G.P. Utility of Diagnostic Imaging in the Diagnosis and Management of Schistosomiasis |
title | Utility of Diagnostic Imaging in the Diagnosis and Management of Schistosomiasis |
title_full | Utility of Diagnostic Imaging in the Diagnosis and Management of Schistosomiasis |
title_fullStr | Utility of Diagnostic Imaging in the Diagnosis and Management of Schistosomiasis |
title_full_unstemmed | Utility of Diagnostic Imaging in the Diagnosis and Management of Schistosomiasis |
title_short | Utility of Diagnostic Imaging in the Diagnosis and Management of Schistosomiasis |
title_sort | utility of diagnostic imaging in the diagnosis and management of schistosomiasis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124748/ https://www.ncbi.nlm.nih.gov/pubmed/25110719 http://dx.doi.org/10.4172/2327-5073.1000142 |
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