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Nuclear reprogramming by interphase cytoplasm of 2-cell mouse embryos
Successful mammalian cloning employing somatic cell nuclear transfer (SCNT) into unfertilized, metaphase II-arrested (MII) oocytes attests to the cytoplasmic presence of reprogramming factors capable of inducing pluripotency in somatic cell nuclei(1-3). However, these poorly defined maternal factors...
Autores principales: | Kang, Enugu, Wu, Guangming, Ma, Hong, Li, Ying, Tippner-Hedges, Rebecca, Tachibana, Masahito, Sparman, Michelle, Wolf, Don P., Schöler, Hans, Mitalipov, Shoukhrat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124901/ https://www.ncbi.nlm.nih.gov/pubmed/24670652 http://dx.doi.org/10.1038/nature13134 |
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