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Nuclear reprogramming by interphase cytoplasm of 2-cell mouse embryos

Successful mammalian cloning employing somatic cell nuclear transfer (SCNT) into unfertilized, metaphase II-arrested (MII) oocytes attests to the cytoplasmic presence of reprogramming factors capable of inducing pluripotency in somatic cell nuclei(1-3). However, these poorly defined maternal factors...

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Detalles Bibliográficos
Autores principales: Kang, Enugu, Wu, Guangming, Ma, Hong, Li, Ying, Tippner-Hedges, Rebecca, Tachibana, Masahito, Sparman, Michelle, Wolf, Don P., Schöler, Hans, Mitalipov, Shoukhrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124901/
https://www.ncbi.nlm.nih.gov/pubmed/24670652
http://dx.doi.org/10.1038/nature13134

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