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A Hepatitis C Virus Infection Model with Time-Varying Drug Effectiveness: Solution and Analysis
Simple models of therapy for viral diseases such as hepatitis C virus (HCV) or human immunodeficiency virus assume that, once therapy is started, the drug has a constant effectiveness. More realistic models have assumed either that the drug effectiveness depends on the drug concentration or that the...
Autores principales: | Conway, Jessica M., Perelson, Alan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125050/ https://www.ncbi.nlm.nih.gov/pubmed/25101902 http://dx.doi.org/10.1371/journal.pcbi.1003769 |
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