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Demography and the Age of Rare Variants

Large whole-genome sequencing projects have provided access to much rare variation in human populations, which is highly informative about population structure and recent demography. Here, we show how the age of rare variants can be estimated from patterns of haplotype sharing and how these ages can...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Mathieson, Iain, McVean, Gil
Format: Online Artikel Text
Sprache:English
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125085/
https://www.ncbi.nlm.nih.gov/pubmed/25101869
http://dx.doi.org/10.1371/journal.pgen.1004528