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Demography and the Age of Rare Variants

Large whole-genome sequencing projects have provided access to much rare variation in human populations, which is highly informative about population structure and recent demography. Here, we show how the age of rare variants can be estimated from patterns of haplotype sharing and how these ages can...

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Detalhes bibliográficos
Autores principales: Mathieson, Iain, McVean, Gil
Formato: Online Artigo Texto
Idioma:English
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125085/
https://www.ncbi.nlm.nih.gov/pubmed/25101869
http://dx.doi.org/10.1371/journal.pgen.1004528