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Demography and the Age of Rare Variants

Large whole-genome sequencing projects have provided access to much rare variation in human populations, which is highly informative about population structure and recent demography. Here, we show how the age of rare variants can be estimated from patterns of haplotype sharing and how these ages can...

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Bibliografske podrobnosti
Autores principales: Mathieson, Iain, McVean, Gil
Format: Online Artículo Texto
Jezik:English
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125085/
https://www.ncbi.nlm.nih.gov/pubmed/25101869
http://dx.doi.org/10.1371/journal.pgen.1004528