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Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress

Homeostatic temperature regulation is fundamental to mammalian physiology and is controlled by acute and chronic responses of local, endocrine and nervous regulators. Here, we report that loss of the heparan sulfate proteoglycan, syndecan-1, causes a profoundly depleted intradermal fat layer, which...

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Detalles Bibliográficos
Autores principales: Kasza, Ildiko, Suh, Yewseok, Wollny, Damian, Clark, Rod J., Roopra, Avtar, Colman, Ricki J., MacDougald, Ormond A., Shedd, Timothy A., Nelson, David W., Yen, Mei-I, Yen, Chi-Liang Eric, Alexander, Caroline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125098/
https://www.ncbi.nlm.nih.gov/pubmed/25101993
http://dx.doi.org/10.1371/journal.pgen.1004514