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Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress
Homeostatic temperature regulation is fundamental to mammalian physiology and is controlled by acute and chronic responses of local, endocrine and nervous regulators. Here, we report that loss of the heparan sulfate proteoglycan, syndecan-1, causes a profoundly depleted intradermal fat layer, which...
Autores principales: | Kasza, Ildiko, Suh, Yewseok, Wollny, Damian, Clark, Rod J., Roopra, Avtar, Colman, Ricki J., MacDougald, Ormond A., Shedd, Timothy A., Nelson, David W., Yen, Mei-I, Yen, Chi-Liang Eric, Alexander, Caroline M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125098/ https://www.ncbi.nlm.nih.gov/pubmed/25101993 http://dx.doi.org/10.1371/journal.pgen.1004514 |
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