Comprehensive Identification of Single Nucleotide Polymorphisms Associated with Beta-lactam Resistance within Pneumococcal Mosaic Genes

Traditional genetic association studies are very difficult in bacteria, as the generally limited recombination leads to large linked haplotype blocks, confounding the identification of causative variants. Beta-lactam antibiotic resistance in Streptococcus pneumoniae arises readily as the bacteria ca...

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Detalles Bibliográficos
Autores principales: Chewapreecha, Claire, Marttinen, Pekka, Croucher, Nicholas J., Salter, Susannah J., Harris, Simon R., Mather, Alison E., Hanage, William P., Goldblatt, David, Nosten, Francois H., Turner, Claudia, Turner, Paul, Bentley, Stephen D., Parkhill, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125147/
https://www.ncbi.nlm.nih.gov/pubmed/25101644
http://dx.doi.org/10.1371/journal.pgen.1004547

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