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Exendin-4 Reduces Ischemic Brain Injury in Normal and Aged Type 2 Diabetic Mice and Promotes Microglial M2 Polarization

Exendin-4 is a glucagon-like receptor 1 agonist clinically used against type 2 diabetes that has also shown neuroprotective effects in experimental stroke models. However, while the neuroprotective efficacy of Exendin-4 has been thoroughly investigated if the pharmacological treatment starts before...

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Detalles Bibliográficos
Autores principales:	Darsalia, Vladimer, Hua, Sansan, Larsson, Martin, Mallard, Carina, Nathanson, David, Nyström, Thomas, Sjöholm, Åke, Johansson, Maria E., Patrone, Cesare
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125154/ https://www.ncbi.nlm.nih.gov/pubmed/25101679 http://dx.doi.org/10.1371/journal.pone.0103114

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