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A Risk Assessment Model for Type 2 Diabetes in Chinese
AIMS: To develop a risk assessment model for persons at risk from type 2 diabetes in Chinese. MATERIALS AND METHODS: The model was generated from the cross-sectional data of 16246 persons aged from 20 years old and over. C4.5 algorithm and multivariate logistic regression were used for variable sele...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125170/ https://www.ncbi.nlm.nih.gov/pubmed/25101994 http://dx.doi.org/10.1371/journal.pone.0104046 |
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author | Luo, Senlin Han, Longfei Zeng, Ping Chen, Feng Pan, Limin Wang, Shu Zhang, Tiemei |
author_facet | Luo, Senlin Han, Longfei Zeng, Ping Chen, Feng Pan, Limin Wang, Shu Zhang, Tiemei |
author_sort | Luo, Senlin |
collection | PubMed |
description | AIMS: To develop a risk assessment model for persons at risk from type 2 diabetes in Chinese. MATERIALS AND METHODS: The model was generated from the cross-sectional data of 16246 persons aged from 20 years old and over. C4.5 algorithm and multivariate logistic regression were used for variable selection. Relative risk value combined with expert decision constructed a comprehensive risk assessment for evaluating the individual risk category. The validity of the model was tested by cross validation and a survey performed six years later with some participants. RESULTS: Nine variables were selected as risk variables. A mathematical model was established to calculate the average probability of diabetes in each cluster's group divided by sex and age. A series of criteria combined with relative RR value (2.2) and level of risk variables stratified individuals into four risk groups (non, low, medium and high risk). The overall accuracy reached 90.99% evaluated by cross-validation inside the model population. The incidence of diabetes for each risk group increased from 1.5 (non-risk group) to 28.2(high-risk group) per one thousand persons per year with six years follow-up. DISCUSSION: The model could determine the individual risk for type 2 diabetes by four risk degrees. This model could be used as a technique tool not only to support screening persons at different risk, but also to evaluate the result of the intervention. |
format | Online Article Text |
id | pubmed-4125170 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-41251702014-08-12 A Risk Assessment Model for Type 2 Diabetes in Chinese Luo, Senlin Han, Longfei Zeng, Ping Chen, Feng Pan, Limin Wang, Shu Zhang, Tiemei PLoS One Research Article AIMS: To develop a risk assessment model for persons at risk from type 2 diabetes in Chinese. MATERIALS AND METHODS: The model was generated from the cross-sectional data of 16246 persons aged from 20 years old and over. C4.5 algorithm and multivariate logistic regression were used for variable selection. Relative risk value combined with expert decision constructed a comprehensive risk assessment for evaluating the individual risk category. The validity of the model was tested by cross validation and a survey performed six years later with some participants. RESULTS: Nine variables were selected as risk variables. A mathematical model was established to calculate the average probability of diabetes in each cluster's group divided by sex and age. A series of criteria combined with relative RR value (2.2) and level of risk variables stratified individuals into four risk groups (non, low, medium and high risk). The overall accuracy reached 90.99% evaluated by cross-validation inside the model population. The incidence of diabetes for each risk group increased from 1.5 (non-risk group) to 28.2(high-risk group) per one thousand persons per year with six years follow-up. DISCUSSION: The model could determine the individual risk for type 2 diabetes by four risk degrees. This model could be used as a technique tool not only to support screening persons at different risk, but also to evaluate the result of the intervention. Public Library of Science 2014-08-07 /pmc/articles/PMC4125170/ /pubmed/25101994 http://dx.doi.org/10.1371/journal.pone.0104046 Text en © 2014 Luo et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Luo, Senlin Han, Longfei Zeng, Ping Chen, Feng Pan, Limin Wang, Shu Zhang, Tiemei A Risk Assessment Model for Type 2 Diabetes in Chinese |
title | A Risk Assessment Model for Type 2 Diabetes in Chinese |
title_full | A Risk Assessment Model for Type 2 Diabetes in Chinese |
title_fullStr | A Risk Assessment Model for Type 2 Diabetes in Chinese |
title_full_unstemmed | A Risk Assessment Model for Type 2 Diabetes in Chinese |
title_short | A Risk Assessment Model for Type 2 Diabetes in Chinese |
title_sort | risk assessment model for type 2 diabetes in chinese |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125170/ https://www.ncbi.nlm.nih.gov/pubmed/25101994 http://dx.doi.org/10.1371/journal.pone.0104046 |
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