Recurrent Arterial and Venous Thromboemboli as Initial Presentation of Acute Promyelocytic Leukemia

We report a case of a 52-year-old Caucasian woman diagnosed with a synchronic arterial and venous thrombosis as an initial presentation of an acute promyelocytic leukemia (APL). After the diagnosis, the patient was treated with all trans-retinoic acid and arsenic chemotherapy concomitant to systemic...

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Autores principales: Trottier-Tellier, Felix, Durand, Madeleine, Kolan, Christophe, Wistaff, Robert, Nguyen, Paul Van, Laskine, Mikhael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125336/
https://www.ncbi.nlm.nih.gov/pubmed/25110545
http://dx.doi.org/10.14740/jocmr1864w
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author Trottier-Tellier, Felix
Durand, Madeleine
Kolan, Christophe
Wistaff, Robert
Nguyen, Paul Van
Laskine, Mikhael
author_facet Trottier-Tellier, Felix
Durand, Madeleine
Kolan, Christophe
Wistaff, Robert
Nguyen, Paul Van
Laskine, Mikhael
author_sort Trottier-Tellier, Felix
collection PubMed
description We report a case of a 52-year-old Caucasian woman diagnosed with a synchronic arterial and venous thrombosis as an initial presentation of an acute promyelocytic leukemia (APL). After the diagnosis, the patient was treated with all trans-retinoic acid and arsenic chemotherapy concomitant to systemic anticoagulation. This treatment regimen led to a complete remission and absence of relapse of the thrombosis or APL during the follow-up. To our knowledge, this presentation is the second case in the literature. We use this opportunity to emphasize the importance of performing a complete medical evaluation in cases of unusual thromboembolic events.
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spelling pubmed-41253362014-08-08 Recurrent Arterial and Venous Thromboemboli as Initial Presentation of Acute Promyelocytic Leukemia Trottier-Tellier, Felix Durand, Madeleine Kolan, Christophe Wistaff, Robert Nguyen, Paul Van Laskine, Mikhael J Clin Med Res Case Report We report a case of a 52-year-old Caucasian woman diagnosed with a synchronic arterial and venous thrombosis as an initial presentation of an acute promyelocytic leukemia (APL). After the diagnosis, the patient was treated with all trans-retinoic acid and arsenic chemotherapy concomitant to systemic anticoagulation. This treatment regimen led to a complete remission and absence of relapse of the thrombosis or APL during the follow-up. To our knowledge, this presentation is the second case in the literature. We use this opportunity to emphasize the importance of performing a complete medical evaluation in cases of unusual thromboembolic events. Elmer Press 2014-10 2014-07-28 /pmc/articles/PMC4125336/ /pubmed/25110545 http://dx.doi.org/10.14740/jocmr1864w Text en Copyright 2014, Trottier-Tellier et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Trottier-Tellier, Felix
Durand, Madeleine
Kolan, Christophe
Wistaff, Robert
Nguyen, Paul Van
Laskine, Mikhael
Recurrent Arterial and Venous Thromboemboli as Initial Presentation of Acute Promyelocytic Leukemia
title Recurrent Arterial and Venous Thromboemboli as Initial Presentation of Acute Promyelocytic Leukemia
title_full Recurrent Arterial and Venous Thromboemboli as Initial Presentation of Acute Promyelocytic Leukemia
title_fullStr Recurrent Arterial and Venous Thromboemboli as Initial Presentation of Acute Promyelocytic Leukemia
title_full_unstemmed Recurrent Arterial and Venous Thromboemboli as Initial Presentation of Acute Promyelocytic Leukemia
title_short Recurrent Arterial and Venous Thromboemboli as Initial Presentation of Acute Promyelocytic Leukemia
title_sort recurrent arterial and venous thromboemboli as initial presentation of acute promyelocytic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125336/
https://www.ncbi.nlm.nih.gov/pubmed/25110545
http://dx.doi.org/10.14740/jocmr1864w
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