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Linking tumor hypoxia with VEGFR2 signaling and compensatory angiogenesis: Glycans make the difference
Although blocking vascular endothelial growth factor (VEGF) signaling is clinically beneficial in certain cancers, tumor regrowth in treated patients suggests that compensatory angiogenic programs may limit the efficacy of anti-VEGF treatment. We found that association of galectin-1 with complex N-g...
Autores principales: | Croci, Diego O, Rabinovich, Gabriel A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125380/ https://www.ncbi.nlm.nih.gov/pubmed/25114834 http://dx.doi.org/10.4161/onci.29380 |
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