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Nidovirus papain-like proteases: Multifunctional enzymes with protease, deubiquitinating and deISGylating activities
Coronaviruses and arteriviruses, members of the order Nidovirales, are positive strand RNA viruses that encode large replicase polyproteins that are processed by viral proteases to generate the nonstructural proteins which mediate viral RNA synthesis. The viral papain-like proteases (PLPs) are criti...
Autores principales: | Mielech, Anna M., Chen, Yafang, Mesecar, Andrew D., Baker, Susan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125544/ https://www.ncbi.nlm.nih.gov/pubmed/24512893 http://dx.doi.org/10.1016/j.virusres.2014.01.025 |
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