ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2

BACKGROUND: ΔNp63, a splice variant of p63, is overexpressed and exhibits oncogenic activity in many cancers including pancreatic and breast cancer and promotes cell survival by inhibiting apoptosis. Despite its role in tumorigenesis, mechanistic activity of ΔNp63 mediated oncogenic function in oste...

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Detalles Bibliográficos
Autores principales: Ram Kumar, Ram Mohan, Betz, Michael M, Robl, Bernhard, Born, Walter, Fuchs, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125704/
https://www.ncbi.nlm.nih.gov/pubmed/25085524
http://dx.doi.org/10.1186/1471-2407-14-559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125704/
https://www.ncbi.nlm.nih.gov/pubmed/25085524
http://dx.doi.org/10.1186/1471-2407-14-559

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