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ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2
BACKGROUND: ΔNp63, a splice variant of p63, is overexpressed and exhibits oncogenic activity in many cancers including pancreatic and breast cancer and promotes cell survival by inhibiting apoptosis. Despite its role in tumorigenesis, mechanistic activity of ΔNp63 mediated oncogenic function in oste...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125704/ https://www.ncbi.nlm.nih.gov/pubmed/25085524 http://dx.doi.org/10.1186/1471-2407-14-559 |