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Crystal structures of the S6K1 kinase domain in complexes with inhibitors

Ribosomal protein S6 kinase 1 (S6K1) is a serine/threonine protein kinase that plays an important role in the PIK3/mTOR signaling pathway, and is implicated in diseases including diabetes, obesity, and cancer. The crystal structures of the S6K1 kinase domain in complexes with staurosporine and the S...

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Detalles Bibliográficos
Autores principales:	Niwa, Hideaki, Mikuni, Junko, Sasaki, Shunta, Tomabechi, Yuri, Honda, Keiko, Ikeda, Mariko, Ohsawa, Noboru, Wakiyama, Motoaki, Handa, Noriko, Shirouzu, Mikako, Honma, Teruki, Tanaka, Akiko, Yokoyama, Shigeyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125821/ https://www.ncbi.nlm.nih.gov/pubmed/25078151 http://dx.doi.org/10.1007/s10969-014-9188-8

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