Persistent prion infection disturbs the function of Oct-1, resulting in the down-regulation of murine interferon regulatory factor-3

As a prompt response against invasion of various viruses, interferon regulatory factor-3 (IRF-3) is initially phosphorylated to become activated and upregulates mainly Type I Interferons (IFN-I) in most cell types. We previously reported that IRF-3-dependent host innate immune responses partially in...

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Detalles Bibliográficos
Autores principales: Homma, Takujiro, Ishibashi, Daisuke, Nakagaki, Takehiro, Fuse, Takayuki, Sano, Kazunori, Satoh, Katsuya, Atarashi, Ryuichiro, Nishida, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126003/
https://www.ncbi.nlm.nih.gov/pubmed/25103253
http://dx.doi.org/10.1038/srep06006

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