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Prospects for novel inhibitors of peptidoglycan transglycosylases

The lack of novel antimicrobial drugs under development coupled with the increasing occurrence of resistance to existing antibiotics by community and hospital acquired infections is of grave concern. The targeting of biosynthesis of the peptidoglycan component of the bacterial cell wall has proven t...

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Detalles Bibliográficos
Autores principales: Galley, Nicola F., O’Reilly, Amy M., Roper, David I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126109/
https://www.ncbi.nlm.nih.gov/pubmed/24924926
http://dx.doi.org/10.1016/j.bioorg.2014.05.007

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