Cargando…

LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis

Transcriptional elongation by RNA polymerase (Pol) II is essential for gene expression during cell growth and differentiation. The positive transcription elongation factor b (P-TEFb) stimulates transcriptional elongation by phosphorylating Pol II and antagonizing negative elongation factors. A reser...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, Xiaodan, Lu, Huasong, Zhou, Qiang, Luo, Kunxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126343/
https://www.ncbi.nlm.nih.gov/pubmed/25053741
http://dx.doi.org/10.7554/eLife.02907