Cargando…

The ubiquitin proteasome system in glia and its role in neurodegenerative diseases

The ubiquitin proteasome system (UPS) is crucial for intracellular protein homeostasis and for degradation of aberrant and damaged proteins. The accumulation of ubiquitinated proteins is a hallmark of many neurodegenerative diseases, including amyotrophic lateral sclerosis, Alzheimer’s, Parkinson’s,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jansen, Anne H. P., Reits, Eric A. J., Hol, Elly M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126450/ https://www.ncbi.nlm.nih.gov/pubmed/25152710 http://dx.doi.org/10.3389/fnmol.2014.00073

Ejemplares similares

Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases
por: Zheng, Qiuyang, et al.
Publicado: (2016)

The Ubiquitin-Proteasome System in Huntington's Disease: Are Proteasomes Impaired, Initiators of Disease, or Coming to the Rescue?
por: Schipper-Krom, Sabine, et al.
Publicado: (2012)

The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution
por: Dantuma, Nico P., et al.
Publicado: (2014)

Role of Glia-Derived Extracellular Vesicles in Neurodegenerative Diseases
por: Li, Tianbai, et al.
Publicado: (2021)

Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation
por: Lindsten, Kristina, et al.
Publicado: (2002)

Ubiquitin-Proteasome System in Neurodegenerative Disorders
por: Rao, Geeta, et al.
Publicado: (2015)

Detection of ubiquitinated huntingtin species in intracellular aggregates
por: Juenemann, Katrin, et al.
Publicado: (2015)

Ubiquitin–proteasome system involvement in Huntington’s disease
por: Ortega, Zaira, et al.
Publicado: (2014)

Roles of the ubiquitin proteasome system in the effects of drugs of abuse
por: Massaly, Nicolas, et al.
Publicado: (2015)

Unstructured Biology of Proteins from Ubiquitin-Proteasome System: Roles in Cancer and Neurodegenerative Diseases
por: Gadhave, Kundlik, et al.
Publicado: (2020)

Ubiquitin pathways in neurodegenerative disease
por: Atkin, Graham, et al.
Publicado: (2014)

An optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes
por: Ristic, Gorica, et al.
Publicado: (2014)

Exploration on the Mechanism of Ubiquitin Proteasome System in Cerebral Stroke
por: Li, Yu-Chao, et al.
Publicado: (2022)

The Ubiquitination, Disaggregation and Proteasomal Degradation Machineries in Polyglutamine Disease
por: Nath, Samir R., et al.
Publicado: (2017)

Role of the ubiquitin proteasome system in Alzheimer's disease
por: Upadhya, Sudarshan C, et al.
Publicado: (2007)

Role of the ubiquitin proteasome system in Parkinson's disease
por: Lim, Kah-Leong, et al.
Publicado: (2007)

The Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer’s Disease and Spinal Cord Injury
por: Gong, Bing, et al.
Publicado: (2016)

Perturbations of Ubiquitin-Proteasome-Mediated Proteolysis in Aging and Alzheimer’s Disease
por: Hegde, Ashok N., et al.
Publicado: (2019)

Involvement of the ubiquitin-proteasome system in the expression of extracellular matrix genes in retinal pigment epithelial cells
por: Ramos de Carvalho, J. Emanuel, et al.
Publicado: (2018)

Ubiquitin–proteasome system and the role of its inhibitors in cancer therapy
por: Aliabadi, Fatemeh, et al.
Publicado: (2021)

Ubiquitin Proteasome System in Stress and Disease
por: Karpov, Dmitry, et al.
Publicado: (2012)

The Multifaceted Role of the Ubiquitin Proteasome System in Pathogenesis and Diseases
por: Stekel, Zane, et al.
Publicado: (2022)

Aß Pathology and Neuron–Glia Interactions: A Synaptocentric View
por: Huffels, Christiaan F. M., et al.
Publicado: (2022)

Strategies to Investigate Ubiquitination in Huntington's Disease
por: Sap, Karen A., et al.
Publicado: (2020)

Radial glia and radial glia-like cells: Their role in neurogenesis and regeneration
por: Miranda-Negrón, Yamil, et al.
Publicado: (2022)

Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell‐type‐specific
por: Jansen, Anne H.P., et al.
Publicado: (2016)

A Putative Role for Ubiquitin-Proteasome Signaling in Estrogenic Memory Regulation
por: Beamish, Sarah B., et al.
Publicado: (2022)

The ubiquitin-proteasome system in Alzheimer's disease
por: Oddo, Salvatore
Publicado: (2008)

Rev-erbs and Glia—Implications for Neurodegenerative Diseases
por: Griffin, Percy, et al.
Publicado: (2019)

Endoplasmic reticulum stress and ubiquitin-proteasome system impairment in natural scrapie
por: Lozada Ortiz, Jenny, et al.
Publicado: (2023)

Interplay Between the Autophagy-Lysosomal Pathway and the Ubiquitin-Proteasome System: A Target for Therapeutic Development in Alzheimer’s Disease
por: Bustamante, Hianara A., et al.
Publicado: (2018)

Localization of mutant ubiquitin in the brain of a transgenic mouse line with proteasomal inhibition and its validation at specific sites in Alzheimer's disease
por: Gentier, Romina J. G., et al.
Publicado: (2015)

Targeting Ubiquitin-Proteasome Pathway by Natural Products: Novel Therapeutic Strategy for Treatment of Neurodegenerative Diseases
por: Momtaz, Saeideh, et al.
Publicado: (2020)

Role of Glia in Memory Deficits Following Traumatic Brain Injury: Biomarkers of Glia Dysfunction
por: Sajja, Venkata S. S. S., et al.
Publicado: (2016)

The ubiquitin proteasome system in Caenorhabditis elegans and its regulation()
por: Papaevgeniou, Nikoletta, et al.
Publicado: (2014)

Editorial: The role of glia in plasticity and behavior
por: Hoogland, Tycho M., et al.
Publicado: (2015)

The ubiquitin proteasome system in neuropathology
por: Lehman, Norman L.
Publicado: (2009)

Neurodegenerative disorders: the Glia way forward
por: Barker, Roger A., et al.
Publicado: (2014)

Dysfunctional glia: contributors to neurodegenerative disorders
por: Sidoryk-Węgrzynowicz, Marta, et al.
Publicado: (2020)

Muscle wasting in chronic kidney disease: the role of the ubiquitin proteasome system and its clinical impact
por: Rajan, Vik R., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_p0bs0kc29q4nofu3rlm7ov89m9