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Long-term functional duration of immune responses to HCV NS3/4A induced by DNA vaccination

We have investigated the ability of hepatitis C virus non-structural (NS) 3/4A-DNA-based vaccines to activate long-term cell-mediated immune responses in mice. Wild-type and synthetic codon optimized (co) NS3/4A DNA vaccines have previously been shown to be immunogenic in mice, rabbits and humans, a...

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Detalles Bibliográficos
Autores principales:	Ahlén, G, Holmström, F, Gibbs, A, Alheim, M, Frelin, L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126484/ https://www.ncbi.nlm.nih.gov/pubmed/24871581 http://dx.doi.org/10.1038/gt.2014.48

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