Cytoplasmic nanojunctions between lysosomes and sarcoplasmic reticulum are required for specific calcium signaling

Herein we demonstrate how nanojunctions between lysosomes and sarcoplasmic reticulum (L-SR junctions) serve to couple lysosomal activation to regenerative, ryanodine receptor-mediated cellular Ca (2+) waves. In pulmonary artery smooth muscle cells (PASMCs) it has been proposed that nicotinic acid ad...

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Detalles Bibliográficos
Autores principales: Fameli, Nicola, Ogunbayo, Oluseye A., van Breemen, Cornelis, Evans, A. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126599/
https://www.ncbi.nlm.nih.gov/pubmed/25126414
http://dx.doi.org/10.12688/f1000research.3720.1

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