Correlation of Molecular Markers, Pfmdr1-N86Y and Pfcrt-K76T, with In Vitro Chloroquine Resistant Plasmodium falciparum, Isolated in the Malaria Endemic States of Assam and Arunachal Pradesh, Northeast India

The mechanism of chloroquine (CQ) resistance in Plasmodium falciparum is not clearly understood. However, CQ resistance has been shown to be associated with point mutations in Pfcrt and Pfmdr1. These genes encode for digestive vacuole transmembrane proteins Pfcrt and Pgh1, respectively. The present...

Descripción completa

Detalles Bibliográficos
Autores principales: Shrivastava, Sandeep Kumar, Gupta, Ravi Kumar, Mahanta, Jagdish, Dubey, Mohan Lal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126653/
https://www.ncbi.nlm.nih.gov/pubmed/25105963
http://dx.doi.org/10.1371/journal.pone.0103848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126653/
https://www.ncbi.nlm.nih.gov/pubmed/25105963
http://dx.doi.org/10.1371/journal.pone.0103848

Ejemplares similares