The rs225017 Polymorphism in the 3′UTR of the Human DIO2 Gene Is Associated with Increased Insulin Resistance

The Thr92Ala (rs225014) polymorphism in the type 2 deiodinase (DIO2) gene has been associated with insulin resistance (IR) and decreased enzyme activity in human tissues but kinetic studies failed to detect changes in the mutant enzyme, suggesting that this variant might be a marker of abnormal DIO2...

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Detalles Bibliográficos
Autores principales: Leiria, Leonardo B., Dora, José M., Wajner, Simone M., Estivalet, Aline A. F., Crispim, Daisy, Maia, Ana Luiza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126657/
https://www.ncbi.nlm.nih.gov/pubmed/25105294
http://dx.doi.org/10.1371/journal.pone.0103960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126657/
https://www.ncbi.nlm.nih.gov/pubmed/25105294
http://dx.doi.org/10.1371/journal.pone.0103960

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