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Delta-Opioid Receptor Analgesia Is Independent of Microglial Activation in a Rat Model of Neuropathic Pain
The analgesic effect of delta-opioid receptor (DOR) ligands in neuropathic pain is not diminished in contrast to other opioid receptor ligands, which lose their effectiveness as analgesics. In this study, we examine whether this effect is related to nerve injury-induced microglial activation. We the...
Autores principales: | Mika, Joanna, Popiolek-Barczyk, Katarzyna, Rojewska, Ewelina, Makuch, Wioletta, Starowicz, Katarzyna, Przewlocka, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126741/ https://www.ncbi.nlm.nih.gov/pubmed/25105291 http://dx.doi.org/10.1371/journal.pone.0104420 |
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