Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation

Although oxidative tissue injury often accompanies viral infection, there is little understanding of how it influences virus replication. We show that multiple hepatitis C virus (HCV) genotypes are exquisitely sensitive to oxidative membrane damage, a property distinguishing them from other pathogen...

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Detalles Bibliográficos
Autores principales: Yamane, Daisuke, McGivern, David R., Wauthier, Eliane, Yi, MinKyung, Madden, Victoria J., Welsch, Christoph, Antes, Iris, Wen, Yahong, Chugh, Pauline E., McGee, Charles E., Widman, Douglas G., Misumi, Ichiro, Bandyopadhyay, Sibali, Kim, Seungtaek, Shimakami, Tetsuro, Oikawa, Tsunekazu, Whitmire, Jason K., Heise, Mark T., Dittmer, Dirk P., Kao, C. Cheng, Pitson, Stuart M, Merrill, Alfred H., Reid, Lola M., Lemon, Stanley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126843/
https://www.ncbi.nlm.nih.gov/pubmed/25064127
http://dx.doi.org/10.1038/nm.3610

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