Intracellular Calcium Regulates Nonsense-Mediated mRNA Decay

The nonsense-mediated mRNA decay (NMD) pathway selectively eliminates aberrant transcripts containing premature translation termination codons (PTCs) and regulates the levels of a number of physiological mRNAs. NMD modulates the clinical outcome of a variety of human diseases, including cancer and m...

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Detalles Bibliográficos
Autores principales: Nickless, Andrew, Jackson, Erin, Marasa, Jayne, Nugent, Patrick, Mercer, Robert W., Piwnica-Worms, David, You, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126864/
https://www.ncbi.nlm.nih.gov/pubmed/25064126
http://dx.doi.org/10.1038/nm.3620

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