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Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review
Coronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127220/ https://www.ncbi.nlm.nih.gov/pubmed/25136365 http://dx.doi.org/10.1155/2014/413920 |
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author | Boukhris, Marouane Tomasello, Salvatore Davide Marzà, Francesco Bregante, Sonia Pluchinotta, Francesca Romana Galassi, Alfredo Ruggero |
author_facet | Boukhris, Marouane Tomasello, Salvatore Davide Marzà, Francesco Bregante, Sonia Pluchinotta, Francesca Romana Galassi, Alfredo Ruggero |
author_sort | Boukhris, Marouane |
collection | PubMed |
description | Coronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in women than in men. It was established that the deficiency of endogenous estrogens promotes the atherosclerosis process. However, the impact of estrogen replacement therapy (ERT) on cardiovascular prevention remains controversial. Some authors strongly recommend it, whereas others revealed a concerning trend toward harm. This review tries to underlines the different components of cardiovascular risk in diabetic PMW and to define the place of ERT. |
format | Online Article Text |
id | pubmed-4127220 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-41272202014-08-18 Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review Boukhris, Marouane Tomasello, Salvatore Davide Marzà, Francesco Bregante, Sonia Pluchinotta, Francesca Romana Galassi, Alfredo Ruggero Int J Endocrinol Review Article Coronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in women than in men. It was established that the deficiency of endogenous estrogens promotes the atherosclerosis process. However, the impact of estrogen replacement therapy (ERT) on cardiovascular prevention remains controversial. Some authors strongly recommend it, whereas others revealed a concerning trend toward harm. This review tries to underlines the different components of cardiovascular risk in diabetic PMW and to define the place of ERT. Hindawi Publishing Corporation 2014 2014-07-17 /pmc/articles/PMC4127220/ /pubmed/25136365 http://dx.doi.org/10.1155/2014/413920 Text en Copyright © 2014 Marouane Boukhris et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Boukhris, Marouane Tomasello, Salvatore Davide Marzà, Francesco Bregante, Sonia Pluchinotta, Francesca Romana Galassi, Alfredo Ruggero Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
title | Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
title_full | Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
title_fullStr | Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
title_full_unstemmed | Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
title_short | Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
title_sort | coronary heart disease in postmenopausal women with type ii diabetes mellitus and the impact of estrogen replacement therapy: a narrative review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127220/ https://www.ncbi.nlm.nih.gov/pubmed/25136365 http://dx.doi.org/10.1155/2014/413920 |
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