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Anandamide Protects HT22 Cells Exposed to Hydrogen Peroxide by Inhibiting CB1 Receptor-Mediated Type 2 NADPH Oxidase

Background. Endogenous cannabinoid anandamide (AEA) protects neurons from oxidative injury in rodent models; however the mechanism of AEA-induced neuroprotection remains to be determined. Activation of neuronal NADPH oxidase 2 (Nox2) contributes to oxidative damage of the brain, and inhibition of No...

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Detalles Bibliográficos
Autores principales: Jia, Ji, Ma, Lei, Wu, Mingchun, Zhang, Lei, Zhang, Xiajing, Zhai, Qian, Jiang, Tao, Wang, Qiang, Xiong, Lize
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127243/
https://www.ncbi.nlm.nih.gov/pubmed/25136404
http://dx.doi.org/10.1155/2014/893516

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