Cargando…
Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial
This study investigated the effects of a pragmatic lifestyle intervention in obese adults with continuous positive airway pressure-treated obstructive sleep apnoea hypopnoea syndrome (OSAHS). Sixty patients were randomised 1 : 1 to either a 12-week lifestyle intervention or an advice-only control gr...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127266/ https://www.ncbi.nlm.nih.gov/pubmed/25136550 http://dx.doi.org/10.1155/2014/102164 |
_version_ | 1782330010566131712 |
---|---|
author | Moss, James Tew, Garry Alan Copeland, Robert James Stout, Martin Billings, Catherine Grant Saxton, John Michael Winter, Edward Mitchell Bianchi, Stephen Mark |
author_facet | Moss, James Tew, Garry Alan Copeland, Robert James Stout, Martin Billings, Catherine Grant Saxton, John Michael Winter, Edward Mitchell Bianchi, Stephen Mark |
author_sort | Moss, James |
collection | PubMed |
description | This study investigated the effects of a pragmatic lifestyle intervention in obese adults with continuous positive airway pressure-treated obstructive sleep apnoea hypopnoea syndrome (OSAHS). Sixty patients were randomised 1 : 1 to either a 12-week lifestyle intervention or an advice-only control group. The intervention involved supervised exercise sessions, dietary advice, and the promotion of lifestyle behaviour change using cognitive-behavioural techniques. Outcomes were assessed at baseline (week 0), intervention end-point (week 13), and follow-up (week 26). The primary outcome was 13-week change in body mass. Secondary outcomes included anthropometry, blood-borne biomarkers, exercise capacity, and health-related quality of life. At end-point, the intervention group exhibited small reductions in body mass (−1.8 [−3.0, −0.5] kg; P = 0.007) and body fat percentage (−1 [−2, 0]%; P = 0.044) and moderate improvements in C-reactive protein (−1.3 [−2.4, −0.2] mg·L(−1); P = 0.028) and exercise capacity (95 [50, 139] m; P < 0.001). At follow-up, changes in body mass (−2.0 [−3.5, −0.5] kg; P = 0.010), body fat percentage (−1 [−2, 0]%; P = 0.033), and C-reactive protein (−1.3 [−2.5, −0.1] mg·L(−1); P = 0.037) were maintained and exercise capacity was further improved (132 [90, 175] m; P < 0.001). This trial is registered with ClinicalTrials.gov NCT01546792. |
format | Online Article Text |
id | pubmed-4127266 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-41272662014-08-18 Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial Moss, James Tew, Garry Alan Copeland, Robert James Stout, Martin Billings, Catherine Grant Saxton, John Michael Winter, Edward Mitchell Bianchi, Stephen Mark Biomed Res Int Clinical Study This study investigated the effects of a pragmatic lifestyle intervention in obese adults with continuous positive airway pressure-treated obstructive sleep apnoea hypopnoea syndrome (OSAHS). Sixty patients were randomised 1 : 1 to either a 12-week lifestyle intervention or an advice-only control group. The intervention involved supervised exercise sessions, dietary advice, and the promotion of lifestyle behaviour change using cognitive-behavioural techniques. Outcomes were assessed at baseline (week 0), intervention end-point (week 13), and follow-up (week 26). The primary outcome was 13-week change in body mass. Secondary outcomes included anthropometry, blood-borne biomarkers, exercise capacity, and health-related quality of life. At end-point, the intervention group exhibited small reductions in body mass (−1.8 [−3.0, −0.5] kg; P = 0.007) and body fat percentage (−1 [−2, 0]%; P = 0.044) and moderate improvements in C-reactive protein (−1.3 [−2.4, −0.2] mg·L(−1); P = 0.028) and exercise capacity (95 [50, 139] m; P < 0.001). At follow-up, changes in body mass (−2.0 [−3.5, −0.5] kg; P = 0.010), body fat percentage (−1 [−2, 0]%; P = 0.033), and C-reactive protein (−1.3 [−2.5, −0.1] mg·L(−1); P = 0.037) were maintained and exercise capacity was further improved (132 [90, 175] m; P < 0.001). This trial is registered with ClinicalTrials.gov NCT01546792. Hindawi Publishing Corporation 2014 2014-07-21 /pmc/articles/PMC4127266/ /pubmed/25136550 http://dx.doi.org/10.1155/2014/102164 Text en Copyright © 2014 James Moss et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Moss, James Tew, Garry Alan Copeland, Robert James Stout, Martin Billings, Catherine Grant Saxton, John Michael Winter, Edward Mitchell Bianchi, Stephen Mark Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial |
title | Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial |
title_full | Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial |
title_fullStr | Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial |
title_full_unstemmed | Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial |
title_short | Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial |
title_sort | effects of a pragmatic lifestyle intervention for reducing body mass in obese adults with obstructive sleep apnoea: a randomised controlled trial |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127266/ https://www.ncbi.nlm.nih.gov/pubmed/25136550 http://dx.doi.org/10.1155/2014/102164 |
work_keys_str_mv | AT mossjames effectsofapragmaticlifestyleinterventionforreducingbodymassinobeseadultswithobstructivesleepapnoeaarandomisedcontrolledtrial AT tewgarryalan effectsofapragmaticlifestyleinterventionforreducingbodymassinobeseadultswithobstructivesleepapnoeaarandomisedcontrolledtrial AT copelandrobertjames effectsofapragmaticlifestyleinterventionforreducingbodymassinobeseadultswithobstructivesleepapnoeaarandomisedcontrolledtrial AT stoutmartin effectsofapragmaticlifestyleinterventionforreducingbodymassinobeseadultswithobstructivesleepapnoeaarandomisedcontrolledtrial AT billingscatherinegrant effectsofapragmaticlifestyleinterventionforreducingbodymassinobeseadultswithobstructivesleepapnoeaarandomisedcontrolledtrial AT saxtonjohnmichael effectsofapragmaticlifestyleinterventionforreducingbodymassinobeseadultswithobstructivesleepapnoeaarandomisedcontrolledtrial AT winteredwardmitchell effectsofapragmaticlifestyleinterventionforreducingbodymassinobeseadultswithobstructivesleepapnoeaarandomisedcontrolledtrial AT bianchistephenmark effectsofapragmaticlifestyleinterventionforreducingbodymassinobeseadultswithobstructivesleepapnoeaarandomisedcontrolledtrial |