Cargando…

The Neuromuscular Junction: Aging at the Crossroad between Nerves and Muscle

Aging is associated with a progressive loss of muscle mass and strength and a decline in neurophysiological functions. Age-related neuromuscular junction (NMJ) plays a key role in musculoskeletal impairment that occurs with aging. However, whether changes in the NMJ precede or follow the decline of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gonzalez-Freire, Marta, de Cabo, Rafael, Studenski, Stephanie A., Ferrucci, Luigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127816/ https://www.ncbi.nlm.nih.gov/pubmed/25157231 http://dx.doi.org/10.3389/fnagi.2014.00208

Ejemplares similares

Degeneration of Neuromuscular Junction in Age and Dystrophy
por: Rudolf, Rüdiger, et al.
Publicado: (2014)

Neuromuscular Junction as an Entity of Nerve-Muscle Communication
por: Lepore, Elisa, et al.
Publicado: (2019)

Diabetes, Muscles, and the Myth of Ulysses' Bow
por: Ferrucci, Luigi, et al.
Publicado: (2009)

The Aging Brain: Crossroad of Normal Aging and Dementia
por: Tian, Qu, et al.
Publicado: (2020)

Dissection of the Transversus Abdominis Muscle for Whole-mount Neuromuscular Junction Analysis
por: Murray, Lyndsay, et al.
Publicado: (2014)

FOXO Regulates Neuromuscular Junction Homeostasis During Drosophila Aging
por: Birnbaum, Allison, et al.
Publicado: (2021)

Impairment Mechanisms and Intervention Approaches for Aged Human Neuromuscular Junctions
por: Badawi, Yomna, et al.
Publicado: (2020)

Early body composition, but not body mass, is associated with future accelerated decline in muscle quality
por: Fabbri, Elisa, et al.
Publicado: (2017)

Gene Expression Profile at the Motor Endplate of the Neuromuscular Junction of Fast-Twitch Muscle
por: Huang, Kun, et al.
Publicado: (2020)

Ultrafast endocytosis at Caenorhabditis elegans neuromuscular junctions
por: Watanabe, Shigeki, et al.
Publicado: (2013)

Motoneuron Wnts regulate neuromuscular junction development
por: Shen, Chengyong, et al.
Publicado: (2018)

DMT1 Expression and Iron Levels at the Crossroads Between Aging and Neurodegeneration
por: Ingrassia, Rosaria, et al.
Publicado: (2019)

Synaptic Activity and Muscle Contraction Increases PDK1 and PKCβI Phosphorylation in the Presynaptic Membrane of the Neuromuscular Junction
por: Hurtado, Erica, et al.
Publicado: (2017)

Searching for a mitochondrial root to the decline in muscle function with ageing
por: Gonzalez‐Freire, Marta, et al.
Publicado: (2018)

The Neuromuscular Junction: Roles in Aging and Neuromuscular Disease
por: Iyer, Shama R., et al.
Publicado: (2021)

Shared Resistance to Aging and ALS in Neuromuscular Junctions of Specific Muscles
por: Valdez, Gregorio, et al.
Publicado: (2012)

Dissecting and Recording from The C. Elegans Neuromuscular Junction
por: Richmond, Janet
Publicado: (2009)

Arhgef5 Binds α-Dystrobrevin 1 and Regulates Neuromuscular Junction Integrity
por: Bernadzki, Krzysztof M., et al.
Publicado: (2020)

Fine Localization of Acetylcholinesterase in the Synaptic Cleft of the Vertebrate Neuromuscular Junction
por: Blotnick-Rubin, Edna, et al.
Publicado: (2018)

Denervation-Related Neuromuscular Junction Changes: From Degeneration to Regeneration
por: Huang, Xinying, et al.
Publicado: (2022)

Autophagy Impairment in Muscle Induces Neuromuscular Junction Degeneration and Precocious Aging
por: Carnio, Silvia, et al.
Publicado: (2014)

Measuring biological aging in humans: A quest
por: Ferrucci, Luigi, et al.
Publicado: (2019)

The role of oxidative stress in degeneration of the neuromuscular junction in amyotrophic lateral sclerosis
por: Pollari, Eveliina, et al.
Publicado: (2014)

Neuromuscular Junctions in Flight and Tymbal Muscles of the Cicada
por: Edwards, George A., et al.
Publicado: (1958)

Neuromuscular Junctions as Key Contributors and Therapeutic Targets in Spinal Muscular Atrophy
por: Boido, Marina, et al.
Publicado: (2016)

Adducin at the Neuromuscular Junction in Amyotrophic Lateral Sclerosis: Hanging on for Dear Life
por: Krieger, Charles, et al.
Publicado: (2016)

Neuromuscular Junction Impairment in Amyotrophic Lateral Sclerosis: Reassessing the Role of Acetylcholinesterase
por: Campanari, Maria-Letizia, et al.
Publicado: (2016)

Why Quantification Matters: Characterization of Phenotypes at the Drosophila Larval Neuromuscular Junction
por: Sanhueza, Mario, et al.
Publicado: (2016)

Lack of Desmin in Mice Causes Structural and Functional Disorders of Neuromuscular Junctions
por: Eiber, Nane, et al.
Publicado: (2020)

The TOR Pathway at the Neuromuscular Junction: More Than a Metabolic Player?
por: Castets, Perrine, et al.
Publicado: (2020)

PXF-1 promotes synapse development at the neuromuscular junction in Caenorhabditis elegans
por: Lamb, Reagan, et al.
Publicado: (2022)

Remnant neuromuscular junctions in denervated muscles contribute to functional recovery in delayed peripheral nerve repair
por: Li, Leyang, et al.
Publicado: (2019)

The transforming growth factor beta ligand TIG-2 modulates the function of neuromuscular junction and muscle energy metabolism in Caenorhabditis elegans
por: Cheng, Xinran, et al.
Publicado: (2022)

Rejuvenation of the aged neuromuscular junction by exercise
por: Kreko-Pierce, Tabita, et al.
Publicado: (2018)

Adaptive Remodeling of the Neuromuscular Junction with Aging
por: Deschenes, Michael R., et al.
Publicado: (2022)

Insulin-Like Growth Factor 1: At the Crossroads of Brain Development and Aging
por: Wrigley, Sarah, et al.
Publicado: (2017)

Murine muscle stem cell response to perturbations of the neuromuscular junction are attenuated with aging
por: Larouche, Jacqueline A, et al.
Publicado: (2021)

Protocadherins at the Crossroad of Signaling Pathways
por: Pancho, Anna, et al.
Publicado: (2020)

Generation of Functional Neuromuscular Junctions from Human Pluripotent Stem Cell Lines
por: Puttonen, Katja A., et al.
Publicado: (2015)

Impaired Mitophagy Plays a Role in Denervation of Neuromuscular Junctions in ALS Mice
por: Rogers, Robert S., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_q59b2ssug6mvv9c8kgjsvtbg69