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IgA dominant postinfectious glomerulonephritis: Report of two cases

Immunoglobulin A (IgA) dominant postinfectious glomerulonephritis (IgA PIGN) is a distinct clinical entity increasingly recognized in adult. It usually presents with reduced glomerular filtration rate, heavy proteinuria, and has unfavorable prognosis. Immunofluorescence study of renal biopsy specime...

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Autores principales: Rajakumar, V., Mohamed, S. A. K. Noor, Kurien, A. A., Fernando, M. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127840/
https://www.ncbi.nlm.nih.gov/pubmed/25120298
http://dx.doi.org/10.4103/0971-4065.132020
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author Rajakumar, V.
Mohamed, S. A. K. Noor
Kurien, A. A.
Fernando, M. E.
author_facet Rajakumar, V.
Mohamed, S. A. K. Noor
Kurien, A. A.
Fernando, M. E.
author_sort Rajakumar, V.
collection PubMed
description Immunoglobulin A (IgA) dominant postinfectious glomerulonephritis (IgA PIGN) is a distinct clinical entity increasingly recognized in adult. It usually presents with reduced glomerular filtration rate, heavy proteinuria, and has unfavorable prognosis. Immunofluorescence study of renal biopsy specimens have IgA as dominant or codominant antibody. We encountered two cases of IgA dominant PIGN recently presenting as rapidly progr essive glomerulonephritis and managed conservatively. Both the patients are on follow-up and do not have complete recovery of renal function till date. Long-term follow-up is needed to assess the progression of the disease in these patients.
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spelling pubmed-41278402014-08-12 IgA dominant postinfectious glomerulonephritis: Report of two cases Rajakumar, V. Mohamed, S. A. K. Noor Kurien, A. A. Fernando, M. E. Indian J Nephrol Case Report Immunoglobulin A (IgA) dominant postinfectious glomerulonephritis (IgA PIGN) is a distinct clinical entity increasingly recognized in adult. It usually presents with reduced glomerular filtration rate, heavy proteinuria, and has unfavorable prognosis. Immunofluorescence study of renal biopsy specimens have IgA as dominant or codominant antibody. We encountered two cases of IgA dominant PIGN recently presenting as rapidly progr essive glomerulonephritis and managed conservatively. Both the patients are on follow-up and do not have complete recovery of renal function till date. Long-term follow-up is needed to assess the progression of the disease in these patients. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4127840/ /pubmed/25120298 http://dx.doi.org/10.4103/0971-4065.132020 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Rajakumar, V.
Mohamed, S. A. K. Noor
Kurien, A. A.
Fernando, M. E.
IgA dominant postinfectious glomerulonephritis: Report of two cases
title IgA dominant postinfectious glomerulonephritis: Report of two cases
title_full IgA dominant postinfectious glomerulonephritis: Report of two cases
title_fullStr IgA dominant postinfectious glomerulonephritis: Report of two cases
title_full_unstemmed IgA dominant postinfectious glomerulonephritis: Report of two cases
title_short IgA dominant postinfectious glomerulonephritis: Report of two cases
title_sort iga dominant postinfectious glomerulonephritis: report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127840/
https://www.ncbi.nlm.nih.gov/pubmed/25120298
http://dx.doi.org/10.4103/0971-4065.132020
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