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Investigating G protein signalling bias at the glucagon-like peptide-1 receptor in yeast
BACKGROUND AND PURPOSE: The glucagon-like peptide 1 (GLP-1) receptor performs an important role in glycaemic control, stimulating the release of insulin. It is an attractive target for treating type 2 diabetes. Recently, several reports of adverse side effects following prolonged use of GLP-1 recept...
Autores principales: | Weston, C, Poyner, D, Patel, V, Dowell, S, Ladds, G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128063/ https://www.ncbi.nlm.nih.gov/pubmed/24712679 http://dx.doi.org/10.1111/bph.12716 |
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