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Clonal Progression during the T Cell-Dependent B Cell Antibody Response Depends on the Immunoglobulin D(H) Gene Segment Repertoire

The diversity of the third complementarity determining region of the IgH chain is constrained by natural selection of immunoglobulin diversity (D(H)) sequence. To test the functional significance of this constraint in the context of thymus-dependent (TD) immune responses, we immunized BALB/c mice wi...

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Detalles Bibliográficos
Autores principales:	Trad, Ahmad, Tanasa, Radu Iulian, Lange, Hans, Zemlin, Michael, Schroeder, Harry W., Lemke, Hilmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128299/ https://www.ncbi.nlm.nih.gov/pubmed/25157256 http://dx.doi.org/10.3389/fimmu.2014.00385

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