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Highly Recombinant VGII Cryptococcus gattii Population Develops Clonal Outbreak Clusters through both Sexual Macroevolution and Asexual Microevolution
An outbreak of the fungal pathogen Cryptococcus gattii began in the Pacific Northwest (PNW) in the late 1990s. This outbreak consists of three clonal subpopulations: VGIIa/major, VGIIb/minor, and VGIIc/novel. Both VGIIa and VGIIc are unique to the PNW and exhibit increased virulence. In this study,...
Autores principales: | Billmyre, R. Blake, Croll, Daniel, Li, Wenjun, Mieczkowski, Piotr, Carter, Dee A., Cuomo, Christina A., Kronstad, James W., Heitman, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128362/ https://www.ncbi.nlm.nih.gov/pubmed/25073643 http://dx.doi.org/10.1128/mBio.01494-14 |
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