Focused Specificity of Intestinal Th17 Cells towards Commensal Bacterial Antigens

T-helper-17 (Th17) cells have critical roles in mucosal defense and in autoimmune disease pathogenesis (1-3). They are most abundant in the small intestine lamina propria (SILP), where their presence requires colonization of mice with microbiota (4-7). Segmented Filamentous Bacteria (SFB) are suffic...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Torchinsky, Miriam B., Gobert, Michael, Xiong, Huizhong, Xu, Mo, Linehan, Jonathan L., Alonzo, Francis, Ng, Charles, Chen, Alessandra, Lin, Xiyao, Sczesnak, Andrew, Liao, Jia-Jun, Torres, Victor J., Jenkins, Marc K., Lafaille, Juan J., Littman, Dan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128479/
https://www.ncbi.nlm.nih.gov/pubmed/24739972
http://dx.doi.org/10.1038/nature13279

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