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Blockade of IL-36 Receptor Signaling Does Not Prevent from TNF-Induced Arthritis

INTRODUCTION: Interleukin (IL)-36α is a newly described member of the IL-1 cytokine family with a known inflammatory and pathogenic function in psoriasis. Recently, we could demonstrate that the receptor (IL-36R), its ligand IL-36α and its antagonist IL-36Ra are expressed in synovial tissue of arthr...

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Detalles Bibliográficos
Autores principales:	Derer, Anja, Groetsch, Bettina, Harre, Ulrike, Böhm, Christina, Towne, Jennifer, Schett, Georg, Frey, Silke, Hueber, Axel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128584/ https://www.ncbi.nlm.nih.gov/pubmed/25111378 http://dx.doi.org/10.1371/journal.pone.0101954

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