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Vulvar Cancer in the North of Israel

PURPOSE: This is a population study of patients who were treated for vulvar cancer in a tertiary center in northern Israel, aimed to report clinical findings, treatment, and outcome. METHODS: A retrospective chart review of all medical records of consecutive patients who were treated for vulvar canc...

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Autores principales: Kaidar-Person, Orit, Ibrahim, Nour, Amit, Amnon, Bortnyak-Abdah, Roxolyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rambam Health Care Campus 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128593/
https://www.ncbi.nlm.nih.gov/pubmed/25120922
http://dx.doi.org/10.5041/RMMJ.10156
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author Kaidar-Person, Orit
Ibrahim, Nour
Amit, Amnon
Bortnyak-Abdah, Roxolyana
author_facet Kaidar-Person, Orit
Ibrahim, Nour
Amit, Amnon
Bortnyak-Abdah, Roxolyana
author_sort Kaidar-Person, Orit
collection PubMed
description PURPOSE: This is a population study of patients who were treated for vulvar cancer in a tertiary center in northern Israel, aimed to report clinical findings, treatment, and outcome. METHODS: A retrospective chart review of all medical records of consecutive patients who were treated for vulvar cancer in the years 1993–2012 was conducted. Data extracted from the medical records included demographics, histology, size of lesion, stage of disease at diagnosis, type of treatment, radiation dose, follow-up, recurrence, and survival. RESULTS: The study included 44 patients with a median age of 69.8 years (range, 42–93 years). Thirty-five (79.5%) of the patients were of Jewish descent, five were Arabic, and four were of other descent. The most common histology type was squamous cell carcinoma in 35 (79.5%) patients. Most patients were staged FIGO II–III at time of diagnosis. Surgery was the most common primary treatment modality (54.2%). Twenty-three (52.2%) patients had recurrent disease. Older age and more advanced stage at diagnosis were associated with increased mortality. CONCLUSION: Vulvar cancer is common among elderly women with co-morbidities who present in advanced disease stage; all these factors are significant for survival.
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spelling pubmed-41285932014-08-12 Vulvar Cancer in the North of Israel Kaidar-Person, Orit Ibrahim, Nour Amit, Amnon Bortnyak-Abdah, Roxolyana Rambam Maimonides Med J Clinical Research In Oncology PURPOSE: This is a population study of patients who were treated for vulvar cancer in a tertiary center in northern Israel, aimed to report clinical findings, treatment, and outcome. METHODS: A retrospective chart review of all medical records of consecutive patients who were treated for vulvar cancer in the years 1993–2012 was conducted. Data extracted from the medical records included demographics, histology, size of lesion, stage of disease at diagnosis, type of treatment, radiation dose, follow-up, recurrence, and survival. RESULTS: The study included 44 patients with a median age of 69.8 years (range, 42–93 years). Thirty-five (79.5%) of the patients were of Jewish descent, five were Arabic, and four were of other descent. The most common histology type was squamous cell carcinoma in 35 (79.5%) patients. Most patients were staged FIGO II–III at time of diagnosis. Surgery was the most common primary treatment modality (54.2%). Twenty-three (52.2%) patients had recurrent disease. Older age and more advanced stage at diagnosis were associated with increased mortality. CONCLUSION: Vulvar cancer is common among elderly women with co-morbidities who present in advanced disease stage; all these factors are significant for survival. Rambam Health Care Campus 2014-07-25 /pmc/articles/PMC4128593/ /pubmed/25120922 http://dx.doi.org/10.5041/RMMJ.10156 Text en Copyright: © 2014 Kaidar-Person O, et al. This is an open-access article. All its content, except where otherwise noted, is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research In Oncology
Kaidar-Person, Orit
Ibrahim, Nour
Amit, Amnon
Bortnyak-Abdah, Roxolyana
Vulvar Cancer in the North of Israel
title Vulvar Cancer in the North of Israel
title_full Vulvar Cancer in the North of Israel
title_fullStr Vulvar Cancer in the North of Israel
title_full_unstemmed Vulvar Cancer in the North of Israel
title_short Vulvar Cancer in the North of Israel
title_sort vulvar cancer in the north of israel
topic Clinical Research In Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128593/
https://www.ncbi.nlm.nih.gov/pubmed/25120922
http://dx.doi.org/10.5041/RMMJ.10156
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