Contribution of Human Immunodeficiency Virus Type 1 Minority Variants to Reduced Drug Susceptibility in Patients on an Integrase Strand Transfer Inhibitor-Based Therapy

The role of HIV-1 minority variants on transmission, pathogenesis, and virologic failure to antiretroviral regimens has been explored; however, most studies of low-level HIV-1 drug-resistant variants have focused in single target regions. Here we used a novel HIV-1 genotypic assay based on deep sequ...

Descripción completa

Detalles Bibliográficos
Autores principales: Gibson, Richard M., Weber, Jan, Winner, Dane, Miller, Michael D., Quiñones-Mateu, Miguel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128663/
https://www.ncbi.nlm.nih.gov/pubmed/25110880
http://dx.doi.org/10.1371/journal.pone.0104512

Ejemplares similares

Ejemplares similares