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Generation of Rat-Induced Pluripotent Stem Cells from a New Model of Metabolic Syndrome

We recently characterized DahlS.Z-Lepr(fa)/Lepr(fa) (DS/obese) rats, derived from a cross between Dahl salt-sensitive rats and Zucker rats, as a new animal model of metabolic syndrome (MetS). Although the phenotype of DS/obese rats is similar to that of humans with MetS, the pathophysiological and m...

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Detalles Bibliográficos
Autores principales: Takenaka-Ninagawa, Nana, Kawabata, Yuka, Watanabe, Shogo, Nagata, Kohzo, Torihashi, Shigeko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128712/
https://www.ncbi.nlm.nih.gov/pubmed/25111735
http://dx.doi.org/10.1371/journal.pone.0104462