Dendritic Cell-Mediated, DNA-Based Vaccination against Hepatitis C Induces the Multi-Epitope-Specific Response of Humanized, HLA Transgenic Mice

Hepatitis C virus (HCV) is the etiologic agent of chronic liver disease, hepatitis C. Spontaneous resolution of viral infection is associated with vigorous HLA class I- and class II-restricted T cell responses to multiple viral epitopes. Unfortunately, only 20% of patients clear infection spontaneou...

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Detalles Bibliográficos
Autores principales: Mishra, Sasmita, Lavelle, Bianca J., Desrosiers, Joe, Ardito, Matt T., Terry, Frances, Martin, William D., De Groot, Anne S., Gregory, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128787/
https://www.ncbi.nlm.nih.gov/pubmed/25111185
http://dx.doi.org/10.1371/journal.pone.0104606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128787/
https://www.ncbi.nlm.nih.gov/pubmed/25111185
http://dx.doi.org/10.1371/journal.pone.0104606

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