Cargando…

Development and characterization of magnetic iron oxide nanoparticles with a cisplatin-bearing polymer coating for targeted drug delivery

A highly selective and efficient cancer therapy can be achieved using magnetically directed superparamagnetic iron oxide nanoparticles (SPIONs) bearing a sufficient amount of the therapeutic agent. In this project, SPIONs with a dextran and cisplatin-bearing hyaluronic acid coating were successfully...

Descripción completa

Detalles Bibliográficos
Autores principales:	Unterweger, Harald, Tietze, Rainer, Janko, Christina, Zaloga, Jan, Lyer, Stefan, Dürr, Stephan, Taccardi, Nicola, Goudouri, Ourania-Menti, Hoppe, Alexander, Eberbeck, Dietmar, Schubert, Dirk W, Boccaccini, Aldo R, Alexiou, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128796/ https://www.ncbi.nlm.nih.gov/pubmed/25120363 http://dx.doi.org/10.2147/IJN.S63433

Ejemplares similares

Synthesis and Characterization of Tissue Plasminogen Activator—Functionalized Superparamagnetic Iron Oxide Nanoparticles for Targeted Fibrin Clot Dissolution
por: Heid, Susanne, et al.
Publicado: (2017)

Hypericin-bearing magnetic iron oxide nanoparticles for selective drug delivery in photodynamic therapy
por: Unterweger, Harald, et al.
Publicado: (2015)

Development of a lauric acid/albumin hybrid iron oxide nanoparticle system with improved biocompatibility
por: Zaloga, Jan, et al.
Publicado: (2014)

Selection of potential iron oxide nanoparticles for breast cancer treatment based on in vitro cytotoxicity and cellular uptake
por: Poller, Johanna M, et al.
Publicado: (2017)

Surface Modification of SPIONs in PHBV Microspheres for Biomedical Applications
por: Idris, Maizlinda I., et al.
Publicado: (2018)

Synthesis and Characterization of Citrate-Stabilized Gold-Coated Superparamagnetic Iron Oxide Nanoparticles for Biomedical Applications
por: Stein, René, et al.
Publicado: (2020)

Biocompatibility of Dextran-Coated 30 nm and 80 nm Sized SPIONs towards Monocytes, Dendritic Cells and Lymphocytes
por: Zschiesche, Lisa, et al.
Publicado: (2022)

Treatment Efficiency of Free and Nanoparticle-Loaded Mitoxantrone for Magnetic Drug Targeting in Multicellular Tumor Spheroids
por: Hornung, Annkathrin, et al.
Publicado: (2015)

Different Storage Conditions Influence Biocompatibility and Physicochemical Properties of Iron Oxide Nanoparticles
por: Zaloga, Jan, et al.
Publicado: (2015)

Non-immunogenic dextran-coated superparamagnetic iron oxide nanoparticles: a biocompatible, size-tunable contrast agent for magnetic resonance imaging
por: Unterweger, Harald, et al.
Publicado: (2017)

Tangential Flow Ultrafiltration Allows Purification and Concentration of Lauric Acid-/Albumin-Coated Particles for Improved Magnetic Treatment
por: Zaloga, Jan, et al.
Publicado: (2015)

Cellular effects of paclitaxel-loaded iron oxide nanoparticles on breast cancer using different 2D and 3D cell culture models
por: Lugert, Stephan, et al.
Publicado: (2018)

A novel human artery model to assess the magnetic accumulation of SPIONs under flow conditions
por: Janikowska, Agata, et al.
Publicado: (2017)

Functionalization Of T Lymphocytes With Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles For Magnetically Controlled Immune Therapy
por: Mühlberger, Marina, et al.
Publicado: (2019)

Functionalized Superparamagnetic Iron Oxide Nanoparticles (SPIONs) as Platform for the Targeted Multimodal Tumor Therapy
por: Janko, Christina, et al.
Publicado: (2019)

Magnetic Drug Targeting Reduces the Chemotherapeutic Burden on Circulating Leukocytes
por: Janko, Christina, et al.
Publicado: (2013)

Dextran-coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging: evaluation of size-dependent imaging properties, storage stability and safety
por: Unterweger, Harald, et al.
Publicado: (2018)

Mitoxantrone Loaded Superparamagnetic Nanoparticles for Drug Targeting: A Versatile and Sensitive Method for Quantification of Drug Enrichment in Rabbit Tissues Using HPLC-UV
por: Tietze, Rainer, et al.
Publicado: (2010)

Facile preparation of multifunctional superparamagnetic PHBV microspheres containing SPIONs for biomedical applications
por: Li, Wei, et al.
Publicado: (2016)

Magnetic Accumulation of SPIONs under Arterial Flow Conditions: Effect of Serum and Red Blood Cells
por: Hennig, Till L., et al.
Publicado: (2019)

Strontium-releasing fluorapatite glass-ceramic scaffolds: Structural characterization and in vivo performance
por: Denry, Isabelle, et al.
Publicado: (2018)

Genotoxicity of Superparamagnetic Iron Oxide Nanoparticles in Granulosa Cells
por: Pöttler, Marina, et al.
Publicado: (2015)

Magnetic Removal of Candida albicans Using Salivary Peptide-Functionalized SPIONs
por: Friedrich, Bernhard, et al.
Publicado: (2023)

Loading of Primary Human T Lymphocytes with Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Does Not Impair Their Activation after Polyclonal Stimulation
por: Mühlberger, Marina, et al.
Publicado: (2020)

Drug delivery to atherosclerotic plaques using superparamagnetic iron oxide nanoparticles
por: Matuszak, Jasmin, et al.
Publicado: (2018)

Inert Coats of Magnetic Nanoparticles Prevent Formation of Occlusive Intravascular Co-aggregates With Neutrophil Extracellular Traps
por: Bilyy, Rostyslav, et al.
Publicado: (2018)

Flow cytometry for intracellular SPION quantification: specificity and sensitivity in comparison with spectroscopic methods
por: Friedrich, Ralf P, et al.
Publicado: (2015)

Tissue Plasminogen Activator Binding to Superparamagnetic Iron Oxide Nanoparticle—Covalent Versus Adsorptive Approach
por: Friedrich, Ralf P, et al.
Publicado: (2016)

Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release
por: Friedrich, Bernhard, et al.
Publicado: (2021)

Biomimetic Magnetic Particles for the Removal of Gram-Positive Bacteria and Lipoteichoic Acid
por: Friedrich, Bernhard, et al.
Publicado: (2022)

Plasmid-DNA Delivery by Covalently Functionalized PEI-SPIONs as a Potential ‘Magnetofection’ Agent
por: Stein, René, et al.
Publicado: (2022)

Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Enable a Stable Non-Spilling Loading of T Cells and Their Magnetic Accumulation
por: Boosz, Philipp, et al.
Publicado: (2021)

Superparamagnetic Iron Oxide Nanoparticles Carrying Chemotherapeutics Improve Drug Efficacy in Monolayer and Spheroid Cell Culture by Enabling Active Accumulation
por: Nguyen, Khanh, et al.
Publicado: (2020)

Comparative in vitro and in vivo Evaluation of Different Iron Oxide-Based Contrast Agents to Promote Clinical Translation in Compliance with Patient Safety
por: Unterweger, Harald, et al.
Publicado: (2023)

Mitoxantrone and Mitoxantrone-Loaded Iron Oxide Nanoparticles Induce Cell Death in Human Pancreatic Ductal Adenocarcinoma Cell Spheroids
por: Dinter, Jonas, et al.
Publicado: (2023)

An in silico model of the capturing of magnetic nanoparticles in tumour spheroids in the presence of flow
por: Wirthl, Barbara, et al.
Publicado: (2023)

Critical Offset Magnetic PArticle SpectroScopy for rapid and highly sensitive medical point-of-care diagnostics
por: Vogel, Patrick, et al.
Publicado: (2022)

Analysis of Hypericin-Mediated Effects and Implications for Targeted Photodynamic Therapy
por: Mühleisen, Laura, et al.
Publicado: (2017)

Determining the resolution of a tracer for magnetic particle imaging by means of magnetic particle spectroscopy
por: Remmo, Amani, et al.
Publicado: (2023)

Detection of viral antibodies in camel sera using magnetic particle spectroscopy
por: Friedrich, Bernhard, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e2shef1624ul12g2vdmnvfenct