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On Simplified Global Nonlinear Function for Fitness Landscape: A Case Study of Inverse Protein Folding
The construction of fitness landscape has broad implication in understanding molecular evolution, cellular epigenetic state, and protein structures. We studied the problem of constructing fitness landscape of inverse protein folding or protein design, with the aim to generate amino acid sequences th...
Autores principales: | Xu, Yun, Hu, Changyu, Dai, Yang, Liang, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128808/ https://www.ncbi.nlm.nih.gov/pubmed/25110986 http://dx.doi.org/10.1371/journal.pone.0104403 |
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