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TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1
High levels of transforming growth factor-β (TGFβ) correlate with poor prognosis for patients with prostate cancer and other cancers. TGFβ is a multifunctional cytokine and crucial regulator of cell fate, such as epithelial to mesenchymal transition (EMT), which is implicated in cancer invasion and...
Autores principales: | Thakur, Noopur, Gudey, Shyam Kumar, Marcusson, Anders, Fu, Jing Yi, Bergh, Anders, Heldin, Carl-Henrik, Landström, Marene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128885/ https://www.ncbi.nlm.nih.gov/pubmed/25483191 http://dx.doi.org/10.4161/cc.29339 |
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