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Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA
BACKGROUND: Metformin is a widely used oral hypoglycemizing agent recently proposed as potential anti-cancer drug. In this study we report the antiproliferative effect of metformin treatment in a high risk neuroblastoma cell model, focusing on possible effects associated to different levels of diffe...
Autores principales: | Costa, Delfina, Gigoni, Arianna, Würth, Roberto, Cancedda, Ranieri, Florio, Tullio, Pagano, Aldo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128937/ https://www.ncbi.nlm.nih.gov/pubmed/25120382 http://dx.doi.org/10.1186/1475-2867-14-59 |
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